β-雌二醇(β-Estradiol) : ≥98% |
β-雌二醇(β-Estradiol) | | | | Synonyms: | 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin | | CAS Number: | 50-28-2 | | Empirical Formula (Hill Notation): | C18H24O2 | | Molecular Weight: | 272.38 | | Beilstein Registry Number: | 1914275 | | EC Number: | 200-023-8 | | MDL number: | MFCD00003693 | | PubChem Substance ID: | 24278426 |
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β-雌二醇(β-Estradiol) ：Biochem/physiol Actions The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation. |
β-雌二醇(β-Estradiol) Properties | assay | ≥98% | | mp | 176-180 °C(lit.) | | Gene Information | human ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), GPER(2852), SERPINA6(866) | | | rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775) | | | mouse ... Esr1(13982), Esr2(13983), Esrra(26379) |
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β-雌二醇(β-Estradiol) : Safety | Hazard Codes | T | | Risk Statements | 45 | | Safety Statements | 53-45 | | WGK Germany | 3 | | RTECS | KG2975000 |
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